1st George Trautman, head of the American Association, becomes general manager of Detroit, succeeding Jack Zeller, who retires after 25 years with the Tigers.
2nd The White Sox buy P Alex Carrasquel and SS Fred Vaughan from the Senators. Carrasquel will make only 3 appearances for Chicago before being farmed out. When the Sox acquire his nephew Chico in 1949, the Sox will swap Alex for reliever Luis Aloma, who will act as an interpreter for the young Venezuelan shortstop.
3rd The Red Sox get Rudy York from Detroit in a trade for Eddie Lake.
5th Catcher Walker Cooper goes to the Giants. The sale by the Cardinals for $175,000 is the highest cash deal ever. The Joe Cronin transaction in 1934 and the Dizzy Dean sale in 1938 were larger deals but also involved other players. Cooper was considered the best catcher in the game before his 1945 induction into the Navy following a salary dispute with the team.
6th The Red Sox announce that they have signed a working agreement with the New Orleans Pelicans. The Pelicans are managed by John Peacock, a former Boston catcher.
12th The first professional league game is played in Venezuela, launching the newly constituted 4-team Liga de Beisbol Profesional de Venezuela. The game is won by Magallanes, 5–2.
16th The Dodgers sign their second Negro League player, inking lanky Johnny Wright. Many consider the signing as a way to give Jackie Robinson someone to room with, but Wright is considered a legit prospect. He does not do well in spring training, but makes the roster of the 1946 Montreal team, appearing in two games. In late May 1946 he is demoted to Class C Three Rivers, where he will help the team win the league title by going 12-8. He will be back with the Homestead Grays in 1947, holding the distinction of being the second black ball player signed by Organized Baseball.
22nd The Red Sox sell veteran 3B Jim Tabor to the Phillies.